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Research published in Cancer Biology & Therapy demonstrated that thymosin beta-4 "is overexpressed in human pancreatic cancer cells" and has been shown to "stimulate tumor growth and metastasis by induction of cell migration and vascular endothelial growth factor-mediated angiogenesis." Multiple studies have found thymosin beta-4 upregulated in various cancers, including colorectal, gastric, pancreatic, and non-small cell lung cancer

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